{"product_id":"estalife-ubiquinol-100mg-kaneka-ubiquinol™","title":"Estalife Ubiquinol 100MG Kaneka Ubiquinol™","description":"\u003cdiv\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003e60 Veg Capsules · 60 Days Supply · Vegan · Made in Singapore\u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eWhy the form of CoQ10 you take matters more than the dose\u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eCoQ10 exists in the body in two forms: ubiquinone, the oxidised form, and ubiquinol, the reduced, active antioxidant form. In healthy adults, roughly 95% of the CoQ10 circulating in the blood is already in the ubiquinol form, and the body has to convert ubiquinone into ubiquinol before it can be used the same way. Most conventional CoQ10 supplements use ubiquinone, which means your body still has to do that conversion work. Ubiquinol skips that step, since it's already in the form the body uses. This matters most for people whose CoQ10 levels are already under pressure, as CoQ10 naturally declines with age. For this group, choosing a form that the body can use directly may make it easier for the body to utilise CoQ10.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eWhy Kaneka Ubiquinol™ \u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eKaneka Ubiquinol™ is a patented, yeast-fermented ubiquinol ingredient that is bioidentical to the ubiquinol the body produces naturally. It's manufactured by Kaneka Corporation, the company that first developed a commercially viable process for stabilising ubiquinol outside the body. A human safety and bioavailability study, involving healthy volunteers given single and 4-week repeated doses, found no clinically relevant changes in laboratory tests, vital signs, or ECG readings at any dose tested, and confirmed the ingredient was reliably absorbed into plasma [1].\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eThe evidence for this specific dose is solid. A randomised, double-blind, placebo-controlled trial published in Nutrients (2020) gave adults with mild-to-moderate dyslipidemia either 100mg\/day or 200mg\/day of ubiquinol, or a placebo, for 8 weeks. The 100mg\/day group, the same dose in this product, showed a statistically significant improvement in flow-mediated dilation, a standard measure of how well blood vessels widen in response to increased blood flow, compared with placebo (+1.34%, p\u0026lt;0.001) [2]. Plasma CoQ10 levels also rose significantly in both treated groups, confirming the dose was actually absorbed and used.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eWhat you get per serving \u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eUbiquinol (from Kaneka Ubiquinol™) | 100mg | Daily Value not established\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eServing size: 1 Vegetable Capsule | Servings per container: 60 | Supply: 60 days\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eVegan | Non-GMO | FDA-Registered Facility | Made in Singapore\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eKey Benefits\u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eSupports heart health \u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eIn the 8-week randomised trial described above, 100mg\/day of ubiquinol significantly improved flow-mediated dilation, a marker of healthy blood vessel function, compared with placebo [2]. This reflects support for vascular health markers, not a claim to treat or prevent heart disease.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eSupports energy production \u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eCoQ10, is a required cofactor in the mitochondrial electron transport chain, the pathway your cells use to generate ATP, the body's primary energy currency. This is a well-established, foundational role of CoQ10 in human cell biology, independent of any single clinical trial.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eProvides antioxidant support \u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eUbiquinol is the active antioxidant form of CoQ10. In the same 8-week trial, ubiquinol supplementation was associated with improved resistance of LDL cholesterol to oxidation, one pathway by which antioxidants are thought to support healthy blood vessel function [2]. Separately, a randomised trial in healthy adults found that short-term ubiquinol supplementation reduced markers of oxidative stress associated with strenuous exercise [3], supporting its antioxidant role beyond the cardiovascular context alone.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eSupports reproductive health \u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eSperm cells rely heavily on mitochondria for the energy needed for motility, and are especially vulnerable to oxidative damage. A double-blind, placebo-controlled randomised trial of 228 men with unexplained infertility gave one group 200mg\/day of ubiquinol and the other a placebo for 26 weeks. The ubiquinol group showed significantly higher sperm density, motility, and normal morphology than placebo at the end of treatment [4]. CoQ10 is also essential for healthy egg cells. As women age, CoQ10 levels and oocyte quality may naturally decline. Emerging research suggests that CoQ10 supplementation may support ovarian response and oocyte quality in women undergoing fertility treatment.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eDirections of Use \u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eTake 1 capsule daily with any meal containing healthy fats to enhance absorption, as ubiquinol is a fat-soluble nutrient. Or take as directed by a healthcare professional. Store in a cool and dry place.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\n\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eCaution:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"text-only\"\u003e Individuals with medical conditions should consult a healthcare professional before using any dietary supplements.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eWho is this suitable for?\u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003e-Adults over 40, given the natural age-related decline in the body's own CoQ10 production \u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003e-Adults who want CoQ10 already in its active, bioidentical form, rather than the oxidised form that requires conversion \u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003e-Adults looking for a well-studied antioxidant to pair with their existing cardiovascular or wellness routine\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003e-Vegans and vegetarians, given the vegetable capsule format and yeast-fermented ingredient source\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003e-Men and women looking to support reproductive health and fertility\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eWhy Estalife Ubiquinol 100MG Kaneka Ubiquinol™ ? \u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eKaneka Ubiquinol™ is the most extensively studied branded ubiquinol on the market, already in the active form your body uses. Made and batch tested in our own NSF GMP-certified factory in Ang Mo Kio, Singapore. No middlemen. Sold directly to you.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eThank you for supporting made in Singapore.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eFrequently Asked Questions \u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003e\u003cstrong\u003eQ: What's the difference between ubiquinol and regular CoQ10 (ubiquinone) supplements?\u003c\/strong\u003e \u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eA: Ubiquinone is the oxidised form and needs to be converted by your body before it can function as an antioxidant. Ubiquinol is already in that active, reduced form, which is also the form that makes up about 95% of the CoQ10 circulating in a healthy adult's blood.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003e\u003cstrong\u003eQ: Why do I need to take this with food? \u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eA: Ubiquinol is fat-soluble, meaning it's absorbed better alongside dietary fat. Taking it with a meal that contains healthy fats, as directed on the label, helps your body absorb more of it.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003e\u003cstrong\u003eQ: Does this treat heart disease? \u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eA: No. The clinical evidence we cite shows ubiquinol improved a marker of blood vessel function in an 8-week study. That's meaningfully different from treating or preventing a diagnosed cardiovascular condition, and we want to be upfront about that distinction.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003e\u003cstrong\u003eQ: How long before I notice a difference? \u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cspan class=\"text-only\"\u003eA: The clinical trial we reference measured changes at 4 and 8 weeks, with the significant improvement in vessel function recorded at 8 weeks. Individual experiences with any supplement will vary.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"text-only\"\u003eReferences \u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\n\u003cspan class=\"text-only\"\u003e[1] Hosoe K, Kitano M, Kishida H, et al. Study on Safety and Bioavailability of Ubiquinol (Kaneka QH) After Single and 4-Week Multiple Oral Administration to Healthy Volunteers. Regulatory Toxicology and Pharmacology, 2007, 47(1):19-28 \u003c\/span\u003e\u003ca rel=\"noopener noreferrer\" class=\"link rich-text-anchor __anchor-intercept-flag__\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0273230006001322\" target=\"_blank\"\u003ehttps:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0273230006001322\u003c\/a\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\n\u003cspan class=\"text-only\"\u003e[2] Sabbatinelli J, Orlando P, Galeazzi R, et al. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial. Nutrients, 2020, 12(4):1098 \u003c\/span\u003e\u003ca rel=\"noopener noreferrer\" class=\"link rich-text-anchor __anchor-intercept-flag__\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7231284\/\" target=\"_blank\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7231284\/\u003c\/a\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\n\u003cspan class=\"text-only\"\u003e[3] Sarmiento A, Diaz-Castro J, Pulido-Moran M, et al. Short-Term Ubiquinol Supplementation Reduces Oxidative Stress Associated with Strenuous Exercise in Healthy Adults: A Randomized Trial. Biofactors, 2016, 42(6):612-622 \u003c\/span\u003e\u003ca rel=\"noopener noreferrer\" class=\"link rich-text-anchor __anchor-intercept-flag__\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27193497\/\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/27193497\/\u003c\/a\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"rich-text-paragraph\"\u003e\n\u003cspan class=\"text-only\"\u003e[4] Safarinejad MR, Safarinejad S, Shafiei N, Safarinejad S. Effects of the Reduced Form of Coenzyme Q10 (Ubiquinol) on Semen Parameters in Men with Idiopathic Infertility: A Double-Blind, Placebo Controlled, Randomized Study. Journal of Urology, 2012, 188(2):526-534 \u003c\/span\u003e\u003ca rel=\"noopener noreferrer\" class=\"link rich-text-anchor __anchor-intercept-flag__\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22704112\/\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/22704112\/\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Estalife.com","offers":[{"title":"1 Bottle","offer_id":48911820423422,"sku":"FG0745","price":49.99,"currency_code":"SGD","in_stock":true},{"title":"2 Bottles","offer_id":48911820456190,"sku":"FG0745x2","price":95.99,"currency_code":"SGD","in_stock":true},{"title":"5 Bottles","offer_id":48911820488958,"sku":"FG0745x5","price":229.99,"currency_code":"SGD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0636\/3634\/0990\/files\/KanekaUbiquinol.jpg?v=1788862892","url":"https:\/\/estalife.com\/products\/estalife-ubiquinol-100mg-kaneka-ubiquinol%e2%84%a2","provider":"Estalife.com","version":"1.0","type":"link"}