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Estalife Collagen Peptides 6600mg Zero Sugar

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What is it and

its benefits?

The Product: Estalife Collagen Peptides 6600mg (Zero Sugar) is a high-potency, ready-to-drink liquid beauty supplement designed to reverse the structural decline of skin aging using Natural Sweeteners.

How it Works (The "Construction Crew" Analogy): Think of your skin as a building that is slowly cracking.

 The Materials (Collagen 6600mg): We send a massive delivery of "bricks" (Peptides) to the site.
• The Workers (Vitamin C 250mg): The bricks are useless without workers. Vitamin C acts as the "crew" that cements the bricks together.
• The Security Guard (Glutathione): Protects the new structure from damage (UV rays/Pollution) and cleans up the site (Brightening).
 The Clean Fuel (Zero Sugar): Unlike other crews that bring messy junk food (sugar) to the site, this crew works clean—preventing insulin spikes while rebuilding.

35,000+

Boxes sold

4.9 / 5

2,500 REVIEWS

6,600mg

Clinical dose — not 1–2g

Over 70% <1000 Da

Peptide size — highly absorbable

01 . Our certifications & third-party lab tests

Every certificate is issued by an independent body. Every lab report is produced by an accredited third-party laboratory — not us.

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Independently certified. Not self-declared

Our Ang Mo Kio facility holds NSF GMP certification, SOCOTEC GMP certification, and U.S. FDA registration. All three are issued by independent bodies. None are self-declared. This product is also MUIS Halal certified, covering all ingredients, manufacturing processes, machinery, and staff protocols. GMP certification is the international standard for supplement quality.

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Third-party tested. Every batch, every product.

Every batch is independently tested by Eurofins Singapore, one of the world's largest testing laboratory organisations for heavy metals and microbial safety. Raw material purity is also tested by SGS, returning >99.99% β-NMN content. Eurofins also tests our actual product content, returning results confirming our NMN meets label claims.

View all certificates and 3rd party lab reports

Every product's heavy metal and microbial lab reports are publicly available. No sign-in required.

Certificates shown on the linked page are the originals — unedited, directly from the issuing bodies.

02 . Made in Singapore's Largest NSF GMP Certified Supplements Factory

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Our family has been in the nutrition industry for over 20 years. The same manufacturing facility also uses the same machines, ingredients and processes to manufacture supplements and health foods for hospitals, clinics, and global brands. Now with Estalife, we sell directly to you, without the middlemen.

→ Register for a factory tour

Certifications — what they actually mean

NSF GMP Certified

The world's most recognised GMP audit. Auditors flying in yearly for an intense 3 day audit covering all processes, machinery and tracability.

SOCOTEC GMP Certified

Independently verified by a second global standards body. Recognised across Asia and Europe.

FDA-Registered Facility

Registered under U.S. 21 CFR Part 111. Applies to our entire manufacturing site.

MUIS Halal Certified

All ingredients and manufacturing comply with Singapore MUIS Halal standards.

03 . Most collagen products don't use enough — here's what the research actually requires

Clinical studies on skin improvement use 2.5–10g of collagen peptides per day. Most Singapore products use 1–2.5g — enough to print "collagen" on the label, not enough to replicate the doses used in the research that proves it works.

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Proksch et al., Skin Pharmacology and Physiology, 2014

2.5–10g

Daily collagen dose used in published RCTs showing measurable skin elasticity and hydration improvement.

Proksch et al., Skin Pharmacology and Physiology, 2014
Campos et al., Heliyon, 2023

8 wks

Measurable skin elasticity improvement observed at 8 weeks in multiple collagen studies.

Campos et al., Heliyon, 2023

Over 70% <1000 Da

Small molecular weight = efficient intestinal absorption

Seong et al., J Cosmet Dermatol, 2014
Kim et al., Nutrients, 2018

Zero added sugar

A suitable choice for those monitoring their blood sugar levels and managing their weight.

Smith et al., Current Developments in Nutrition, 2025
Anker et al., Nutrients, 2019
Kaim & Labus, Nutrients, 2025

"Collagen peptides work by signalling fibroblasts to produce new collagen. That signal is dose-dependent. Below 2,500mg, the signal is too weak to produce a measurable change."

04 . What's inside — three ingredients that work together

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6,600mg

Hydrolysed Marine Fish Collagen Peptides (Type I)

Derived from deep-sea fish scales and skin. Hydrolysed into peptides as small as 189 Daltons — near the optimal size for intestinal wall absorption. Once absorbed, these peptides signal fibroblasts to produce new collagen and hyaluronic acid. Marine collagen is predominantly Type I, the same type that makes up 80% of skin collagen.

Marine Type I collagen is the most relevant form for skin. The 189 Da peptide size matters — larger fragments are absorbed far less efficiently.

Ohara et al., Journal of Dermatology, 2010
Pu et al., Nutrients, 2014
Asserin et al., Journal of Cosmetic Dermatology, 2015

Ingredients 2.png__PID:676c9512-cae5-4642-850b-127788a69a64

100mcg

L-Glutathione (Reduced Form)

The body's master antioxidant. Glutathione neutralises free radicals and is known to inhibit tyrosinase — the key enzyme involved in melanin production. The reduced form is biologically active form and readily utilised by the body's cells for antioxidant functions. 

Glutathione works together with Vitamin C in the antioxidant recycling network. Vitamin C regenerates oxidised glutathione back to its active reduced form; glutathione reactivates oxidised vitamin C. They are supporting each other simultaneously.

Weschawalit et al., Clin Cosmet Investig Dermatol, 2017
Lee et al., Physical Activity and Nutrition, 2023

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250mg

Vitamin C (Ascorbic Acid)

An essential co-factor in the enzymatic hydroxylation of unfolded procollagen chains to mature functional triple-helix collagen. Vitamin C is not optional - it is a required building material for the process that collagen peptides trigger.

This is why collagen-only products are incomplete. You cannot build new collagen without Vitamin C at an adequate dose.

Telang, Indian Dermatol Online J, 2013
Linus Pauling Institute, Oregon State University — Vitamin C and Skin Health. lpi.oregonstate.edu
Pullar et al., Nutrients, 2017

05 . Key benefits — what the science shows

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Skin elasticity and firmness

Subjects taking 5g daily showed significantly improved skin elasticity at 4 and 8 weeks versus placebo in a double-blind trial.

Proksch et al., Skin Pharmacology and Physiology, 2014

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Skin hydration and moisture

Oral collagen peptides increase skin hydration by stimulating hyaluronic acid production in the dermis. Effects were measurable at 4 weeks in subjects taking collagen peptides daily.

Miyanaga et al., Skin Pharmacology and Physiology, 2021

Supports 3.png__PID:7788a69a-6461-4ff9-a85d-cd04f577bc41

Brightness and even skin tone

Glutathione inhibits tyrosinase, the enzyme driving melanin production. Vitamin C reinforces this through a separate antioxidant pathway. Two mechanisms, one sachet.

Arjinpathana & Asawanonda, Journal of Dermatological Treatment, 2010
Sarkar et al., International Journal of Dermatology, 2024

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Hair and nail strength

Studies show improved hair and scalp condition at daily consumption over 12 weeks. An open-label trial has also showed a 42% reduction in broken nails and a 12% increase in nail growth rate.

Hexsel et al., Journal of Cosmetic Dermatology, 2017
Reilly et al., Dermatology Research and Practice, 2024

06 . Why Jia formulated it this way

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Jia

Estalife Founder

Certified Nutritionist since 2018

100% Singaporean Family-Owned Factory

"I actually made this product for myself too, haha! I've been taking collagen since 2013, and for many of those years I stuck to pure powder with no added sugars. But when the sachet drinks wave came back, it was honestly quite irresistible. They're so much easier to bring around than glass bottles (I was always paranoid about smashing them on travel trips). I still alternate between powder and drinks, but I wanted a sachet version that let me cut down on sugar even further. Our fruit-sugared version is already low at just 1.3g total, but I wanted to push it lower for daily long-term use.

That's what drove this formulation. We used natural non-sugar sweeteners (monk fruit, stevia and erythritol), which won't spike blood sugar like sugar does and have solid recorded safety profiles. Every batch is third-party lab tested before it leaves our facility, same as all our products.

One thing I want to say openly: collagen has a lot of misinformation on both sides. The naysayers claim it's a scam and too big to be absorbed, while some brands oversell it as a miracle protein that can replace your skincare or fix every skin issue. Both are wrong. Collagen as a whole protein is indeed too big to be absorbed, but that's old news. We've had the technology to break it down into collagen peptides (small enough to be efficiently absorbed) for decades, with tons of RCTs proving the cause-and-effect of supplementation. That said, it's not a miracle. Daily sunscreen will do more for long-term skin ageing than daily collagen ever will. Our body is a big complex system, and collagen isn't there to replace anything. It works alongside your diet, exercise and skincare. I'll do a full long-form video on this one day, keep a lookout!

Thank you for all your love so far!"

Why 6,600mg specifically

Middle of the clinical range (2.5–10g). The sweet spot — effective enough to drive real results, refined enough for an enjoyable daily ritual. Above every published minimum effective dose.

Why 500mg Vitamin C — not 30mg

Vitamin C is essential for collagen synthesis. Many brands add 30mg as a token amount. At 250mg, we provide a dose that genuinely supports the process — not a label cosmetic.

Why marine (fish) collagen

Marine collagen is predominantly Type I — the same type that makes up 80% of skin collagen. For skin-focused benefits, marine Type I is the more directly relevant choice.

Why zero sugar

The standard version uses fructose and grape juice concentrate — both contribute to the sweet taste but add sugar. The Zero Sugar variant uses no added sugars or artificial sweeteners, making it suitable for people managing blood sugar or following a lower-sugar diet.

07 . Same ingredient — very different dose and price

3–6×

Most collagen products use 1,000–2,500mg per serving. Clinical studies require at least 2,500mg to show measurable skin improvement. 

WHAT TO CHECKOTHER BRANDSESTALIFE 6,600MGWHY IT MATTERS
Collagen dose1,000–2,500mg6,600mgHuman RCTs demonstrating skin elasticity improvement used 2.5g minimum marin collagen. Estalife delivers 6.6g — the clinical doses in one serving.
Collagen typeOften unspecifiedType I collagenType I is the primary structural collagen in skin. Marine source is predominantly Type I.
Peptide sizeOften unspecifiedOver 70% <1000 DaSmaller peptides cross the gut wall more efficiently. Low molecular weight <1000Da is the optimal range for intestinal absorption.
Vitamin CAbsent or 30–60mg250mg — functional doseWithout Vitamin C, ingested collagen peptides cannot be converted into functional collagen fibre.
GlutathioneAbsent or proprietary blend100mcg reduced (active) formReduced glutathione inhibits tyrosinase — the enzyme responsible for melanin production — and pairs with Vitamin C, which helps regenerate it to its active form.
Added sugarOften presentZero — no added sugarFormulated with natural sweeteners — erythritol, stevia, and monk fruit extract, chosen for their minimal impact on blood glucose. Free from added sugar and artificial sweeteners, making it a suitable daily ritual for those managing blood sugar levels or following a lower-sugar lifestyle.
Price per box$45–$140$29.99We own our own factory and sell directly to you. No distributor or retailer markups.

08 . What to expect — a realistic skin timeline

Collagen works from the inside out. Results are gradual. Here's what the published studies show at each stage.

Week 1–2

Your body gets to work

Collagen peptides are absorbed into the bloodstream within hours of drinking. They travel to the dermis and signal fibroblasts — the skin cells that build collagen and hyaluronic acid — to start producing. Nothing visible yet. But underneath, the rebuild has begun.

Iwai et al., Journal of Agricultural and Food Chemistry, 2005

Week 2–4

Hydration kicks in first

Hyaluronic acid levels in the dermis begin to rise before new collagen fibres become visible. Skin feels softer, less tight. Dryness reduces. That subtle "plumping" effect most people notice first. This is when it starts.

Asserin et al., J Cosmetic Dermatology, 2015

Week 4–8

Firmness and glow become visible

In a double-blind trial, significant elasticity improvement was measured at 4 weeks — with greater gains by week 8. Glutathione begins modulating melanin production in this window, supporting a more even, brighter tone. Results vary by individual baseline.

Proksch et al., Skin Pharmacology, 2014 · Weschawalit et al., Clin Cosmet Investig Dermatol, 2017

Month 3–6

Structure deepens with consistent use

Skin density and dermal matrix continue to improve. Nail brittleness — measured at 24 weeks in published data — reduces meaningfully. This is the window where people around you start to notice. Not just how your skin looks, but how it feels to touch.

Hexsel et al., J Cosmetic Dermatology, 2017 · Proksch et al., Skin Pharmacology, 2014

Individual results vary. These timelines reflect published clinical data — not a guarantee. Visible results depend on age, skin condition, baseline collagen levels, diet, and consistency of use.

09 . How to take it

One sachet daily. Drink directly. Sour grape flavour with no added sugar and artificial sweeteners — a clean, refreshing taste without sweetness.

1

Open the sachet and drink directly.

2

Take daily. The sour grape flavour makes it easy to build a consistent habit without added sugar.

3

Best on an empty stomach. Either in the morning or before bed.

4

Continue for at least 8–12 weeks, as published clinical trials have shown measurable improvements in skin condition within this timeframe.

If you have a fish allergy, consult your doctor before use. Our collagen is derived from deep-sea fish scales. If pregnant, breastfeeding, or on medication, consult a doctor before taking any supplement.

Pairing guide — Jia's beauty stack

Morning — skin and brightening

Collagen Zero Sugar sachet + Whitening Glutathione 500mg capsule. The sachet contains 100mcg glutathione; the standalone capsule provides a higher dedicated brightening dose. Two complementary delivery forms.

If you're also taking NMN

Take NMN 500mg on an empty stomach in the morning, then your collagen with or after breakfast. No interaction — NMN works through NAD+ pathways, collagen through the skin matrix. Completely separate mechanisms.

Hair and nails add-on

Add Biotin + Calcium + Collagen capsules if hair and nail goals are primary. Biotin supports keratin — the protein in hair and nails that collagen alone doesn't directly target.

10 . Frequently asked questions

Why does dose matter so much for collagen?

Hydrolyzed collagen provides amino acids released during digestion, which serve as essential building blocks that fibroblasts use to construct new collagen fibers. It also provides short peptide fragments that act as signaling molecules, stimulating fibroblasts to increase their own production of collagen and hyaluronic acid. This signaling effect is dose-dependent. Published clinical trials showing significant improvements in use doses ranging from 2.5–10g per day.

How long does it take to see results?

Most users notice improved skin texture and hydration between weeks 4-8. Measurable elasticity improvement is typically seen at week 8 in published studies. Hair and nail improvements generally take longer — most clinical data on these endpoints is from 12–24 week trials. Individual results depend on age, skin condition, and consistency of use. Collagen works cumulatively.

Is fish collagen safe if I have a seafood allergy?

If you have a fish allergy, we strongly recommend consulting your doctor or allergist before taking this product. While fish collagen is extensively hydrolysed — which may reduce allergenic potential — we cannot confirm it is safe for individuals with fish allergies, and we do not recommend taking the risk without medical advice. If you have a shellfish allergy (prawns, crab, lobster) only and no sensitivity to fish, the allergen source is different, but we still recommend checking with your doctor first.

Why zero sugar — what's different from the regular version?

The standard Collagen 6,600mg uses fructose and concentrated grape juice as part of its sweet grape juice base. The Zero Sugar variant removes all added sugars. It contains no fructose, no glucose, and no artificial sweeteners. The formula uses natural sweeteners, erythritol, stevia, and monk fruit extract instead. All active ingredients — 6,600mg collagen, 100mcg glutathione, 250mg Vitamin C — are identical across both versions.

Why is your collagen cheaper than pharmacy brands?

We own our factory. Retailers take 40–50% of the price; distributors take 20–30%. We skip both layers. Lower price reflects our direct factory model — not a lower quality ingredient or a smaller dose. Our manufacturing standards are the same as those we apply to hospital and global brand contracts from the same facility.

Can I take this while pregnant or breastfeeding?

While the ingredients are natural nutrients, we always recommend consulting your doctor before starting any new supplement during pregnancy or breastfeeding.

Can I take this with NMN, Magnesium, or other Estalife supplements?

Yes — collagen works through the skin matrix pathway, completely separate from NMN (NAD+ and cellular energy), Magnesium Glycinate (neuromuscular function and sleep), or CoQ10 (mitochondrial energy). No known interactions. Many customers take their collagen sachet in the morning and NMN capsules separately. If you are on prescription medications, check with your doctor as a general precaution.

11 . What customers say

4.9

Verified reviews

85% report improved skin texture within 4 weeks

Skin texture · Zero sugar

"I switched to this from the regular version because I'm watching my sugar intake. Same results — skin looks more even and plump after 6 weeks. Sour grape flavour is refreshing, not too strong."

Amanda T., 38

Verified · Shopee SG

Brightening · Long-term user

"Diabetic so I needed the zero sugar option. So glad this exists. Been on it for 3 months and my skin is noticeably brighter and my nails are stronger. Didn't sacrifice any results."

Linda C., 52

Verified · TikTok Shop

First timer · Low sugar diet

"Was looking for a collagen without sugar. Most brands either use sugar or weird artificial sweeteners. This one has neither. 4 weeks in and skin feels more hydrated. Will continue."

Rachel L., 34

Verified · Lazada SG

Research Sources & Citations

All claims on this page are supported by published human clinical research. Only human RCTs, meta-analyses of human RCTs, and systematic reviews are cited. No animal or in vitro studies are referenced as evidence for product claims.

1

Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacology and Physiology. 2014;27(1):47–55. doi.org/10.1159/000351376

2

Campos LD, Santos Junior VA, Pimentel JD, Carregã GL, Cazarin CB. Collagen supplementation in skin and orthopedic diseases: a review of the literature. Heliyon. 2023;9:e14961. doi.org/10.1016/j.heliyon.2023.e14961

3

Seong SH, Lee YI, Lee J, et al. Low-molecular-weight collagen peptides supplement promotes a healthy skin: a randomized, double-blinded, placebo-controlled study. Journal of Cosmetic Dermatology. 2024;23(2):554–562. doi.org/10.1111/jocd.16026

4

Kim DU, Chung HC, Choi J, Sakai Y, Lee BY. Oral intake of low-molecular-weight collagen peptide improves hydration, elasticity, and wrinkling in human skin: a randomized, double-blind, placebo-controlled study. Nutrients. 2018;10(7):826. doi.org/10.3390/nu10070826

5

Reilly DM, Kynaston L, Naseem S, Proudman E, Laceby D. A clinical trial shows improvement in skin collagen, hydration, elasticity, wrinkles, scalp, and hair condition following 12-week oral intake of a supplement containing hydrolysed collagen. Dermatology Research and Practice. 2024;2024:8752787. doi.org/10.1155/2024/8752787

6

Ohara H, Ichikawa S, Matsumoto H, Akiyama M, Fujimoto N, Kobayashi T, Tajima S. Collagen-derived dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibroblasts. Journal of Dermatology. 2010;37(4):330–338. doi.org/10.1111/j.1346-8138.2010.00827.x

7

Pu SY, Huang YL, Pu CM, et al. Effects of oral collagen for skin anti-aging: a systematic review and meta-analysis. Nutrients. 2023;15(9):2080. doi.org/10.3390/nu15092080

8

Asserin J, Lati E, Shioya T, Prawitt J. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology. 2015;14(4):291–301. doi.org/10.1111/jocd.12174

9

Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P. Glutathione and its antiaging and antimelanogenic effects. Clinical, Cosmetic and Investigational Dermatology. 2017;10:147–153. doi.org/10.2147/CCID.S128339

10

Lee M, Kim E, Ahn H, Son S, Lee H. Oral intake of collagen peptide NS improves hydration, elasticity, desquamation, and wrinkling in human skin: a randomized, double-blinded, placebo-controlled study. Food & Function. 2023;14(7):3196–3207. doi.org/10.1039/D2FO02958H

11

Telang PS. Vitamin C in dermatology. Indian Dermatology Online Journal. 2013;4(2):143–146. doi.org/10.4103/2229-5178.110593

12

Linus Pauling Institute, Oregon State University. Vitamin C and Skin Health. lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-C

13

Miyanaga M, Uchiyama T, Motoyama A, Ochiai N, Ueda O, Ogo M. Oral supplementation of collagen peptides improves skin hydration by increasing the natural moisturizing factor content in the stratum corneum: a randomized, double-blind, placebo-controlled clinical trial. Skin Pharmacology and Physiology. 2021;34(3):115–127. doi.org/10.1159/000513988

14

Arjinpathana N, Asawanonda P. Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study. Journal of Dermatological Treatment. 2012;23(2):97–102. doi.org/10.3109/09546631003801619

15

Sarkar R, Yadav V, Yadav T, Jain P, Mandal I. Glutathione as a skin-lightening agent and in melasma: a systematic review. International Journal of Dermatology. 2025;64:992–1004. doi.org/10.1111/ijd.17535

16

Hexsel D, Zague V, Schunck M, Siega C, Camozzato FO, Oesser S. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. Journal of Cosmetic Dermatology. 2017;16(4):520–526. doi.org/10.1111/jocd.12393

17

Iwai K, Hasegawa T, Taguchi Y, et al. Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates. Journal of Agricultural and Food Chemistry. 2005;53(16):6531–6536. doi.org/10.1021/jf050206p

18

Pullar JM, Carr AC, Vissers MCM. The roles of vitamin C in skin health. Nutrients. 2017;9(8):866. doi.org/10.3390/nu9080866

19

Anker CCB, Rafiq S, Jeppesen PB. Effect of steviol glycosides on human health with emphasis on type 2 diabetic biomarkers: a systematic review and meta-analysis of randomized controlled trials. Nutrients. 2019;11(9):1965. Natural sweetener safety reference. doi.org/10.3390/nu11091965

20

Kaim U, Labus K. Monk fruit extract and sustainable health: a PRISMA-guided systematic review of randomized controlled trials. Nutrients. 2025;17(9):1433. Natural sweetener safety reference. doi.org/10.3390/nu17091433

21

Smith B, Hamann A, Karadimas T, et al. Effects of erythritol and xylitol on glycemic control, insulin sensitivity, and satiety hormones: a systematic review of human intervention studies. Current Developments in Nutrition. 2025;9(2). Natural sweetener safety reference. doi.org/10.1016/j.cdnut.2025.106618