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UTHEVER® NMN 600MG

Healthy Ageing & Longevity

UTHEVER® NMN 600MG

Name: UTHEVER® NMN 600MG
Brand: Estalife Singapore
SKU: FG0702
Price: 39.99 SGD
Availability: InStock
Rating: 3.97 (29 reviews)

$39.99 SGD

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Key Benefits:

1. Supports Cellular Energy Production
NMN replenishes NAD+ — the fuel your mitochondria use to generate cellular energy. This is why many users report feeling more energised and less fatigued with consistent use.

2. Promotes Healthy Ageing
NAD+ plays a central role in activating sirtuins — proteins involved in DNA repair and cellular maintenance. Supporting NAD+ levels is one of the most researched approaches to healthy cellular ageing.

3. Supports Metabolism
The UTHEVER® clinical trial assessed metabolic markers including HOMA-IR (insulin resistance index), with the NMN group showing a favourable trend compared to placebo.

Size: 1 Bottle

1 Bottle
2 Bottles
5 Bottles

Vegan
FDA
GMP

*Disclaimer
Logos were produced while certification was in process. Rest assured that all ingredients and manufacturing have always complied with MUIS Halal standards.

Product Description & Who It Is For

Product Description

What is NAD+ and why does it matter?
NAD+ is a molecule found in every cell of your body. It powers your cells' ability to produce energy, repair DNA, and regulate hundreds of metabolic processes. The problem: NAD+ levels decline naturally with age — and that decline is closely linked to the fatigue, slower recovery, and reduced vitality that many people notice from their mid-30s onward. NMN (Nicotinamide Mononucleotide) is a direct precursor to NAD+. Your body converts NMN into NAD+ efficiently, making it one of the most studied approaches to supporting healthy NAD+ levels as you age.

Why UTHEVER®?
Not all NMN is equal. The NMN market is saturated with products that vary widely in purity, stability, and evidence. Estalife NMN 600MG uses UTHEVER® — a patented, branded NMN ingredient developed by Effepharm (Shanghai) Co., Ltd., and one of the few NMN ingredients backed by a published human clinical trial. In a 60-day randomised, double-blind, placebo-controlled trial in healthy middle-aged adults, UTHEVER® NMN increased NAD+/NADH levels by 38% compared to baseline. Participants also showed improvements in 6-minute walking endurance and quality-of-life scores. The trial results were published in Frontiers in Aging (2022) and peer-reviewed by scientists including professors at Harvard Medical School. UTHEVER® purity: ≥99.8%, verified by independent third-party laboratory testing.

Who It Is For

Adults wanting to support NAD+ levels, which decline with age
Adults noticing lower energy, slower recovery or reduced vitality
Those focused on healthy ageing and cellular health
Middle-aged adults wanting to support physical endurance
Existing NMN users looking to step up to a higher, clinically studied dose

Ingredients

NMN Uthever® (β-Nicotinamide Mononucleotide)

Function: Acts as a precursor to NAD+, supporting cellular energy production, healthy aging, and overall vitality.

Supporting Ingredients: Corn Starch, Magnesium Stearate, Silicon Dioxide

How to Take

Take 2 capsules daily, whenever it fits your routine. For best absorption, take in the morning on an empty stomach. Recommend to cycle 2 months on, 2 weeks off. Or take as directed by a healthcare professional. Store in a cool and dry place.

Caution: Individuals with medical conditions should consult a healthcare professional before use.

Frequently paired with

Estalife Singapore

CoQ10 150MG

$19.99 SGD

Estalife Singapore

CoQ10 Ubiquinol 100mg + Nicotinamide

$39.99 SGD

Estalife Singapore

Kaneka Ubiquinol 100MG

$59.99 SGD

Estalife Singapore

Vitamin B12 Methylcobalamin

$12.99 SGD

UTHEVER® NMN 600MG

$39.99 SGD

The short version

NAD+ runs your cells, and it falls with age

NMN is the most direct precursor your body uses to make NAD+, the coenzyme behind energy production and DNA repair.
600mg, split across 2 capsules

In a 60-day trial comparing 300, 600 and 900mg a day, 600mg produced significantly higher blood NAD+ than 300mg, while 900mg added nothing significant.
Tested as a finished product, not just raw powder

SGS on the finished capsule, and every batch tested for heavy metals and microbials.
We own the factory

No distributor margin, no retailer margin. Made in our own NSF GMP-certified facility in Ang Mo Kio, and sold directly to you.

NAD+ runs your cells, and it falls with age

NMN is the most direct precursor your body uses to make NAD+, the coenzyme behind energy production and DNA repair.

600mg, split across 2 capsules

In a 60-day trial comparing 300, 600 and 900mg a day, 600mg produced significantly higher blood NAD+ than 300mg, while 900mg added nothing significant.

Tested as a finished product, not just raw powder

SGS on the finished capsule, and every batch tested for heavy metals and microbials.

We own the factory

No distributor margin, no retailer margin. Made in our own NSF GMP-certified facility in Ang Mo Kio, and sold directly to you.

Most supplements aren't what the label says

NUS tested 18 NMN products sold in Singapore. Over 80% were not what they claimed.

In 2024, researchers at NUS Yong Loo Lin School of Medicine and Temasek Polytechnic bought 18 NMN supplements on the Singapore market and measured what was actually in them. More than 80% contained less NMN than the label claimed. Three contained no detectable NMN at all.
What that means for you: in this category, price tells you nothing about whether the product is real. An independent lab result is the only thing that does.
US researchers tested 25 melatonin gummies sold for sleep. Nearly 9 in 10 were not what they claimed.

In 2023, researchers from Harvard Medical School and the University of Mississippi bought 25 melatonin gummy products on the US market and measured what was actually in them. 22 of the 25 were labelled inaccurately, with melatonin ranging from 74% to 347% of the stated dose. Only 3 came within 10% of the label. One contained no melatonin at all, just CBD.

What that means for you: the dose on the label is a promise, not a measurement. You could be taking a fraction of what you paid for, or more than three times it. An independent lab result is the only way to know.

NUS tested 18 NMN products sold in Singapore. Over 80% were not what they claimed.

In 2024, researchers at NUS Yong Loo Lin School of Medicine and Temasek Polytechnic bought 18 NMN supplements on the Singapore market and measured what was actually in them. More than 80% contained less NMN than the label claimed. Three contained no detectable NMN at all.

What that means for you: in this category, price tells you nothing about whether the product is real. An independent lab result is the only thing that does.

US researchers tested 25 melatonin gummies sold for sleep. Nearly 9 in 10 were not what they claimed.

In 2023, researchers from Harvard Medical School and the University of Mississippi bought 25 melatonin gummy products on the US market and measured what was actually in them. 22 of the 25 were labelled inaccurately, with melatonin ranging from 74% to 347% of the stated dose. Only 3 came within 10% of the label. One contained no melatonin at all, just CBD.

What that means for you: the dose on the label is a promise, not a measurement. You could be taking a fraction of what you paid for, or more than three times it. An independent lab result is the only way to know.

What we test and why

Microbial & heavy metals

Every single batch we manufacture is tested by Eurofins Singapore for microbial safety and heavy metals before it is released for sale.

Laboratory: Eurofins

Raw material purity

High risk raw materials like NMN are tested for purity before we even use it in our manufacturing process. Our NMN returns greater than 99.99% β-NMN content.

Laboratory: SGS or Eurofins

Finished product content verification

The actual NMN content in our finished capsule is measured to confirm it delivers the stated amount per serving. This is the test almost nobody in the category runs, not just because it is expensive but because it is where underdosed products get caught.

Laboratory: Eurofins

View our lab reports

How much NMN do you actually need?
A trial compared three doses

Current evidence suggests more is not always better. In a randomised, placebo-controlled trial of 80 healthy adults aged 40 to 65, blood NAD+ rose in every NMN group over 60 days. The 600mg group rose significantly more than the 300mg group. Going up to 900mg made no statistically significant difference.

The researchers concluded the effect peaked at 600mg a day. That is why we chose it.

Yi L et al. GeroScience, 2023

Why this matters

26.7

26.7 percent increase in NAD+ levels was observed in the Uthever® group, from 11.3% at day 30 to 38% at day 60, compared with the placebo group's 14.3% rise.

Huang H. Front. Aging, 2022.
145

Metres average gain in a 6-minute endurance walk for the 600mg group by day 60, versus 5m on placebo. Early evidence from a small 60-day trial.

Yi L et al. GeroScience, 2023
0

Serious adverse events in a 4-week safety trial of healthy adults taking 1,250mg a day, about twice our daily dose.
Fukamizu Y, et al. Scientific Reports. 2022

What's in the bottle

Beta-Nicotinamide Mononucleotide (NMN)
NMN is a direct precursor to NAD+ and is rapidly converted into NAD+ through the Salvage pathway after ingestion. In a 60-day clinical trial, doses of 300mg, 600mg and 900mg all produced significant increases in blood NAD levels, with 600mg reaching significantly higher levels than 300mg and 900mg adding no further benefit.

Estalife NMN uses UTHEVER®, a branded NMN from EffePharm, Shanghai.
We also test the finished product, not just the raw material. SGS verify the actual NMN content to confirm that each serving delivers the stated 600mg dosage. This is especially important because NMN can degrade during manufacturing if not handled correctly.
As one of Singapore’s first manufacturers of NMN supplements, our factory has developed specialised manufacturing expertise, backed by third-party laboratory testing.

Key Benefits

Raises Blood NAD+ Levels

Placebo-controlled human trials report higher blood NAD+ with daily NMN. At 600mg, the rise was larger than at 300mg

Yi L et al., GeroScience, 2023

Supports Physical Endurance

Current evidence suggests NMN may support endurance. Walking distance and aerobic measures improved at 600mg in two small trials.

Yi L et al. GeroScience, 2023; Liao B, Zhao Y, Wang D, et al. Journal of the International Society of Sports Nutrition, 2021

May Ease Daytime Tiredness

In a 12-week trial of older adults, NMN improved some measures of drowsiness and fatigue against placebo, with larger effects when taken in the afternoon.

Kim M, Seol J, Sato T, et al. Nutrients, 2022

Supports Muscle Function With Age

Early trials in older adults recorded improvements in walking speed, grip strength and chair-stand performance.

Igarashi M, Nakagawa-Nagahama Y, Miura M, et al. npj Aging, 2022; Kim M, Seol J, Sato T, et al. Nutrients, 2022

Affordable, because there is nobody between us and you

The usual chain

Manufacturer, then brand owner, then distributor, then retailer, then you. Retailers typically take 40 to 50%. Distributors take another 20 to 30%. Every layer is priced into the bottle before it reaches you.
Here at Estalife

We manufacture it and we sell it. There is no brand owner paying us a manufacturing fee and no retailer adding margin on top.
What we did not cut

Same raw material grade, same NSF GMP certified facility, same Eurofins and SGS testing, same processes and machines used for the hospitals and global brands we manufacture for.

Singapore's largest NSF GMP-certified supplements factory

Our Ang Mo Kio facility used to manufacture mainly for hospitals and global brands. Now, we're manufacturing products directly from our factory to you, under our brand Estalife. No middlemen, straight from the manufacturer. Get to know us!

Read our story

Why we made it this way

I actually made this one because so many of you kept asking for a Uthever version, haha! And honestly it was an easy yes, because we already manufacture Uthever NMN products in our own factory anyway.

We dose this at 300mg per capsule on purpose, which gives you 600mg per 2-capsule serving. There's real thinking behind those exact numbers. 300mg is the dose Uthever tested in their own human clinical trial, and 600mg is the dose that came out best when a published trial on Uthever NMN tested a few levels and found 600mg to be the sweet spot with diminishing returns above it. So each capsule maps neatly onto the research: one cap gives you Uthever's tested 300mg, two caps give you the 600mg optimal.This also makes it really easy to adjust. You can step down to 300mg with a single capsule, or step up as needed. Just one dosing tip: if you ever want to go above 600mg in a day, space it out into two separate sittings rather than taking it all at once, so keep any single dose at 600mg or under.

If you read my note on our original NMN, you'll know traceability and testing is the thing I'm most obsessive about with this ingredient (especially after NUS found over 80% of NMN products in Singapore had less NMN than their label claimed). Our standard NMN already goes through two layers of checking before it reaches you: our own testing, and independent third-party labs like Eurofins and SGS. This Uthever version stacks a third layer on top, because Uthever is a branded ingredient that comes with its own testing and certification straight from the source.

So it's the same rigorous Estalife process you already trust, plus an extra branded paper trail baked right in. That makes it the best pick for anyone who wants maximum traceability and peace of mind, all the way down to the raw material itself.raw material itself.Everything else stays exactly as you'd expect from us. Every batch is third-party lab tested before it leaves our facility, same as all our products.Thank you for all your love so far!

Everything else stays exactly as you'd expect from us. Every batch is third-party lab tested before it leaves our facility, same as all our products.

Thank you for all your love so far!

Jia Photo.png__PID:d849fa8f-e56e-4ee2-bf5a-a444848bc059

Jia, Estalife Founder • Certified Nutritionist since 2018

What to expect - a realistic timeline

Day 1-7

Absorption and conversion begins

NMN metabolites are detectable in blood within hours of a dose. NMN itself is rapidly converted, this is the foundation stage, no noticeable effects yet.
Week 2-4

NAD+ levels measurably increase

By day 30, the 600mg group’s average blood NAD+ was about 4.9 times its starting level, and walking distance had already improved against placebo. Some people notice a change in energy.
Week 4-8

Functional shifts may emerge

By day 60, the 600mg group’s blood NAD+ was about 5.7 times its starting level, with walking distance up around 50% from baseline. Lower limb function scores improved, with less drowsiness compared with placebo.

Pair it with

CoQ10 150MG / CoQ10 Ubiquinol / Kaneka Ubiquinol 100MG: A premium energy stack that supports your cells' power supply.

Vitamin B12 Methylcobalamin: Supports energy production and red blood cell formation, helping reduce tiredness.

Omega-3 Fish Oil: Supports heart and brain health alongside cellular energy.

Frequently asked questions

What is the difference between Estalife NMN 500MG and NMN 600MG?

NMN 500MG uses high quality generic NMN ingredient. NMN 600MG uses UTHEVER® — a patented branded NMN from Effepharm that is backed by published human clinical trial and verified at ≥99.8% purity. The 600MG dose per serving also provides 20% more NMN per day. Both are made in our Singapore factory.

How long before I notice a difference?

The UTHEVER® clinical trial measured outcomes at 30 days and 60 days. NAD+ levels showed an 11.3% increase at day 30 and a 38% increase at day 60. Consistent daily use is important - results build over time.

Can I take this with other Estalife products?

NMN pairs well with CoQ10 Ubiquinol (cellular energy), Magnesium Glycinate (muscle recovery and sleep), and Omega-3 (cardiovascular and cellular health). Consult your doctor if you are on medication.

Is UTHEVER® safe?

The clinical trial found no clinically significant adverse effects. Toxicology testing confirmed UTHEVER® is non-mutagenic and has no acute or sub-chronic toxicity at studied doses.

Think you can trust supplement labels? Think again.

A supplement label tells you what a brand says is inside. It can’t tell you whether that’s true.

In many markets, including Singapore, supplements aren’t independently checked against their labels before they’re sold. That’s why, when scientists test supplements against their labels, they keep finding products with far less, far more, or none of what’s claimed.

5 stars: 16 (55%)
4 stars: 3 (10%)
3 stars: 6 (21%)
2 stars: 1 (3%)
1 star: 3 (10%)

I have been taking Estalife NMN 600mg regular and Uthever for the past 3 to 4 months. I do not feel much difference so I am wondering if I need to continue or not.

My hubby and I started taking NMN 600 since 24Jun. I felt very energetic as dont fell sleepy after half day has gone. Used to fall asleep after 1030am while watching my drama series, but now I can stay awake even till past midnight.
I am not sure if this is related to me taking NMN 600. My hands used to be able to scratch my back just below the back shoulder bone. But now I am able to stretch over to the other side of my back. Has my joints become more agile and flexible.
Overall, I like the NMN 600.

I am very energetic, do you think I should take 500 instead of Uthever NMN 600.
I used to take NMN which I bought online from SG Live streamer but the product from Taiwan. That's why I was recommended to take 600 since I ever taken NMN.

Since taking the supplements, I feel much lighter and more energize. Others said that I look much younger compare to my age. I am happy not because others are saying of my look but because the supplements make me feel positive with my daily activities. Thank you, Estalife.

Keep health going strong

Feeling good

So far it helps with concentration. However the 2 weeks break after 2 months of consumption can feel a drastic drop in energy level

Good

No effect at all, seek refund and no one reply me

i don't see, feel same difference at all after consuming say least 3 bottles with regularly.
What benefits did you say there were supposed to bring?
i astro have a few bottles left, can i get a refund?

No feeling after taking almost 2 bottles. I feel the cheaper 500mg has more effect.🤷‍♂️

I feel great…still having energy after my 12-hr night shifts and minus coffee cravings. My LFTs went to normal after so many years 😅.

safe and effective for me, energy was sustained the whole day

Great Product

I feel more energetic during the day and evening.

None think change

Feel stronger. More energy

I took two pills in the morning with empty stomach, ended up with lots of stomach gas. I reduced to one pill and it is not any better.

I have more energy through out the day to focus on my work and fam

feel great.

Very good for me as I felt energised! Will continue.

I tried the 500MG before this and found the 500MG non UTHEVER more suitable for me.

NMN 600MG - Uthever is an excellent supplement, I have consistently taken every morning before breakfast 2 caps without fail. Overall my body conditions has improve my night sleep is better and my energy has also improved, I will continue with this supplement

I am giving it time to feel the difference. 😜

Didn’t really feel much after my 2nd bottle but let see how it goes as I order under monthly subscription

Honestly I really don’t feel much. Not sure if the the product is working too😬

I think the recommended 2 capsules per day is too high for me, affecting my deep sleep cycle.

To me my health improved

Looks good and according to as per advertisement.
Can only reveiw after using rhe item. .

I am still on my first bottle of NMN 600MG, i do feel a little better every morning... will use the second bottle to see if it gets better.

RESEARCH SOURCES & CITATIONS

All claims on this page are supported by published human clinical research. Only human RCTs and meta-analyses of human RCTs are cited. No animal or in vitro studies are referenced as evidence for product claims.

1
Yi L, Maier AB, Tao R, et al. The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial. GeroScience. 2023;45(1):29–43. doi.org/10.1007/s11357-022-00705-1

2
Huang H. A multicentre, randomised, double blind, parallel design, placebo controlled study to evaluate the efficacy and safety of Uthever (NMN supplement), an orally administered supplementation in middle aged and older adults. Frontiers in Aging. 2022;3:851698. doi.org/10.3389/fragi.2022.851698

3
Liao B, Zhao Y, Wang D, et al. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. Journal of the International Society of Sports Nutrition. 2021;18(1):54. doi.org/10.1186/s12970-021-00442-4

4
Fukamizu Y, Uchida Y, Shigekawa A, et al. Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women. Scientific Reports. 2022;12(1):14442. doi.org/10.1038/s41598-022-18272-y

5
Igarashi M, Nakagawa-Nagahama Y, Miura M, et al. Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men. npj Aging. 2022;8:5. doi.org/10.1038/s41514-022-00084-z

6
Kim M, Seol J, Sato T, et al. Effect of 12-week intake of nicotinamide mononucleotide on sleep quality, fatigue, and physical performance in older Japanese adults: a randomized, double-blind placebo-controlled study. Nutrients. 2022;14(4):755. doi.org/10.3390/nu14040755

7
Sandalova E, et al. Assessment of NMN supplement content accuracy in Singapore. GeroScience. 2024;46:5075–5083. doi.org/10.1007/s11357-024-01257-2

8
Irie J, Inagaki E, Fujita M, et al. Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men. Endocrine Journal. 2020;67(2):153–160. doi.org/10.1507/endocrj.EJ19-0313

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The short version

Most supplements aren't what the label says